The Non-Volatile Arithmetic Memory Operator (NV-AMO) including a non-volatile memory cell for storing non-volatile data and a first input terminal for receiving volatile variable data is applied to perform the arithmetic operations over the volatile variable data and the non-volatile data. The NV-AMO can also be configured multiple-times for new computations. The constructions of NV-AMO in Arithmetic Logic Units (ALU) can be applied in DSP (Digital Signal Processor) computations and DNN (Deep Neural Network) computations.