A computer vision-based fastener loosening detection approach is described. A first image is captured at a first time and a second image is captured at a second time. A feature-based image registration is performed to create a third image. An intensity-based image registration is performed to create a fourth image. Registration errors are determined based on a comparison of the first and fourth images. A feature enhancement process is performed on the registration errors to determine whether the fastener has loosened between the first time and the second time.