The present invention provides a display panel and a manufacturing method thereof. The display panel includes a flexible substrate, a buffer layer, a combination insulation layer, recess, an organic insulation layer, and a first wire changing layer. The first wire changing layer is disposed on an upper surface of the organic insulation layer and extends to the combination insulation layer. The present invention removes a through hole in a conventional organic insulation layer, on one hand mitigates the issue of broken lines in the first wire changing layer, and on the other hand mitigates the issue of shorting of adjacent two of wires in the first wire changing layer because of square waveform, sawtooth waveform, triangular waveform, and sinusoidal waveform of an edge line on a side of the first wire changing layer such that stability of the display panel is improved.