Invention Grant
- Patent Title: Particles and compositions comprising the same for transfection
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Application No.: US16484775Application Date: 2018-02-01
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Publication No.: US11357735B2Publication Date: 2022-06-14
- Inventor: Sabrina Belbekhouche , André Pawlak , Djillali Sahali , Benjamin Carbonnier
- Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Applicant Address: FR Paris; FR Creteil; FR Paris; FR Paris
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Current Assignee Address: FR Paris; FR Creteil; FR Paris; FR Paris
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: EP17305115 20170201
- International Application: PCT/EP2018/052553 WO 20180201
- International Announcement: WO2018/141865 WO 20180809
- Main IPC: A61K9/50
- IPC: A61K9/50 ; A61K47/69 ; A61K9/51 ; C12N15/113

Abstract:
The present invention relates to the localized delivery of nucleic acids to cells using polyelectrolyte assemblies in the form of particles that are prepared by layer-by-layer deposition of nucleic acid and specific polycation. It also relates to compositions comprising said particles and methods for the treatment of disorders or diseases by administration of such particles.
Public/Granted literature
- US20200038336A1 PARTICLES AND COMPOSITIONS COMPRISING THE SAME FOR TRANSFECTION Public/Granted day:2020-02-06
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