Invention Grant
- Patent Title: Non-catalytic substrate-selective, p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof
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Application No.: US17231598Application Date: 2021-04-15
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Publication No.: US11357781B2Publication Date: 2022-06-14
- Inventor: Paul S. Shapiro , Alexander D. MacKerell, Jr. , Jeffrey D. Hasday
- Applicant: University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs
- Applicant Address: US MD Baltimore; US DC Washington
- Assignee: University of Maryland, Baltimore,The United States of America as represented by the Department of Veterans Affairs
- Current Assignee: University of Maryland, Baltimore,The United States of America as represented by the Department of Veterans Affairs
- Current Assignee Address: US MD Baltimore; US DC Washington
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: A61K31/5375
- IPC: A61K31/5375 ; A61K31/18 ; A61K31/54 ; A61P31/00 ; A61P19/02 ; A61P29/00 ; A61P35/00
Abstract:
Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.
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