Invention Grant
- Patent Title: Sterile formulation comprising a stable phosphorothioate oligonucleotide
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Application No.: US16483189Application Date: 2018-02-02
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Publication No.: US11357790B2Publication Date: 2022-06-14
- Inventor: Éric Viaud , Antoine Ferry , Carla Missiaen , Jo Vercammen
- Applicant: GENE SIGNAL INTERNATIONAL SA
- Applicant Address: CH Lausanne
- Assignee: GENE SIGNAL INTERNATIONAL SA
- Current Assignee: GENE SIGNAL INTERNATIONAL SA
- Current Assignee Address: CH Lausanne
- Agency: Maier & Maier, PLLC
- Priority: EP17154670 20170203
- International Application: PCT/EP2018/052663 WO 20180202
- International Announcement: WO2018/141908 WO 20180809
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/713 ; A61K47/12 ; A61K47/02 ; A61K47/20 ; A61K9/00 ; A61K9/107 ; A61K9/113 ; C12N15/113
Abstract:
A composition including a phosphorothioate oligonucleotide and at least one fatty acid and/or at least one emulsifying agent, where the composition is sterile and where the composition includes at least one agent including a thiol group and at least one phosphate compound, and the composition can be an ophthalmic composition. The present invention also relates to a method for obtaining the same and to the therapeutic use thereof.
Public/Granted literature
- US20190350963A1 STERILE FORMULATION COMPRISING A STABLE PHOSPHOROTHIOATE OLIGONUCLEOTIDE Public/Granted day:2019-11-21
Information query
