Invention Grant
- Patent Title: Expression of HIV inhibitors by mesenchymal stem cells
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Application No.: US16002604Application Date: 2018-06-07
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Publication No.: US11357866B2Publication Date: 2022-06-14
- Inventor: Stephen E. Braun , Debasis Mondal , Bruce A Bunnell , Narae Lee
- Applicant: The Administrators of the Tulane Educational Fund
- Applicant Address: US LA New Orleans
- Assignee: The Administrators of the Tulane Educational Fund
- Current Assignee: The Administrators of the Tulane Educational Fund
- Current Assignee Address: US LA New Orleans
- Agency: Boulware & Valoir
- Agent Meng-Tien Hsieh
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61K48/00 ; A61K39/42 ; C07K16/10 ; A61P31/18 ; A61K45/06 ; A61K31/513 ; A61K35/28 ; A61K31/683 ; A61K39/00
Abstract:
A composition of matter and method of treating HIV with mesenchymal stem cells (MSC) is disclosed. Specifically, MSCs are transduced with vectors incorporating an anti-viral fusion inhibitor, such as a C46-derived peptide or neutralizing antibody. The transduced MSCs are capable of expression the inhibitor and preventing HIV virus-cell fusion.
Public/Granted literature
- US20180280538A1 EXPRESSION OF HIV INHIBITORS BY MESENCHYMAL STEM CELLS Public/Granted day:2018-10-04
Information query
