Invention Grant
- Patent Title: SMAC mimetics used as IAP inhibitors and use thereof
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Application No.: US16763746Application Date: 2018-11-13
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Publication No.: US11358950B2Publication Date: 2022-06-14
- Inventor: Yingchun Liu , Zhaobing Xu , Lihong Hu , Charles Z. Ding , Xingxun Zhu , Guoping Hu , Jian Li , Shuhui Chen
- Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Applicant Address: CN Jiangsu
- Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee Address: CN Jiangsu
- Agency: Fish & Richardson P.C.
- Priority: CN201711117079.6 20171113
- International Application: PCT/CN2018/115256 WO 20181113
- International Announcement: WO2019/091492 WO 20190516
- Main IPC: C07D403/06
- IPC: C07D403/06 ; C07D403/14 ; C07D413/14 ; C07D471/04 ; A61P35/00

Abstract:
Disclosed are a class of SMAC mimetics used as IAP inhibitors, and in particular disclosed are compounds as shown in formula (I), isomers thereof, and pharmaceutically acceptable salts thereof. The IAP inhibitors are drugs for treating cancers, in particular breast cancer.
Public/Granted literature
- US20210371400A1 SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF Public/Granted day:2021-12-02
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