Invention Grant
- Patent Title: Thermostable variants of T7 RNA polymerase
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Application No.: US16680014Application Date: 2019-11-11
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Publication No.: US11359184B2Publication Date: 2022-06-14
- Inventor: Jennifer Ong , Vladimir Potapov , Kuo-Chan Hung , Haruichi Asahara , Shaorong Chong , George Tzertzinis
- Applicant: New England Biolabs, Inc.
- Applicant Address: US MA Ipswich
- Assignee: New England Biolabs, Inc.
- Current Assignee: New England Biolabs, Inc.
- Current Assignee Address: US MA Ipswich
- Agency: New England Biolabs, Inc
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12Q1/6858
Abstract:
A bacteriophage RNA polymerase variant is provided. In some embodiments, the variant may have increased thermostability relative to the corresponding wild type bacteriophage RNA polymerase and/or wild type T7 RNA polymerase. Compositions, kits and methods that employ the variant are also provided.
Information query
