Invention Grant
- Patent Title: Uses, methods, kits, compositions and antibodies for identifying hematopoietic cell subtypes
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Application No.: US16342354Application Date: 2017-10-17
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Publication No.: US11360087B2Publication Date: 2022-06-14
- Inventor: Luca Basso-Ricci , Luca Biasco , Alessandro Aiuti
- Applicant: Ospedale San Raffaele S.R.L. , Fondazione Telethon
- Applicant Address: IT Milan; IT Rome
- Assignee: Ospedale San Raffaele S.R.L.,Fondazione Telethon
- Current Assignee: Ospedale San Raffaele S.R.L.,Fondazione Telethon
- Current Assignee Address: IT Milan; IT Rome
- Agency: Grimes & Yvon LLP
- Priority: GB1617572 20161017
- International Application: PCT/EP2017/076517 WO 20171017
- International Announcement: WO2018/073267 WO 20180426
- Main IPC: G01N33/569
- IPC: G01N33/569 ; G01N1/28 ; G01N15/14 ; G01N33/58 ; G01N33/49

Abstract:
Use of (i) an anti-CD3 antibody, (ii) an anti-CD56 antibody, (iii) an anti-CD14 antibody, (iv) an anti-CD38 antibody, (v) an anti-CD45 antibody, (vi) an anti-CD90 antibody, (vii) an anti-CD135 antibody, (viii) an anti-CD10 antibody, (ix) an anti-CD11c antibody, (x) an anti-CD19 antibody, (xi) an anti-CD34 antibody, (xii) an anti-CD45RA antibody, (xiii) an anti-CD7 antibody, (xiv) an anti-CD71 antibody, (xv) an anti-CD41/CD61 complex antibody or an anti-CD41 antibody and/or an anti-CD61 antibody (xvi) an anti-CD33 antibody and/or an anti-CD66b antibody, for identifying hematopoietic cell subtypes in an isolated sample, determining the relative frequency of hematopoietic cell subtypes in an isolated sample and/or quantifying the number of cells within hematopoietic cell subtypes in an isolated sample, wherein each of (i) to (xvi) is labelled with a different fluorochrome, wherein when (xvi) is an anti-CD33 antibody and an anti-CD66b antibody, the anti-CD33 antibody and anti-CD66b are labelled with the same fluorochrome, and wherein when (xv) is an anti-CD41 antibody and an anti-CD61 antibody, the anti-CD4 antibody and the anti-CD61 antibody are labelled with the same fluorochrome.
Public/Granted literature
- US20200182870A1 Uses, Methods, Kits, Compositions and Antibodies for Identifying Hematopoietic Cell Subtypes Public/Granted day:2020-06-11
Information query
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