The invention provides a method of manufacturing a display panel and the display panel. The display panel is applied to a display device having a camera, and the display panel includes an alignment film layer, a liquid crystal layer, and a camera hole. The method includes: performing laser treatment to the alignment film layer to obtain a first light transmission hole and performing laser treatment to the liquid crystal layer to obtain a second light transmission hole. The method provided by the invention reduces a difference of amount of ambient light entering at different angles of the alignment film layer and the liquid crystal layer, and thereby improves imaging quality of the camera.