Invention Grant
- Patent Title: Injectable pharmaceutical composition of tecovirimat and preparation method thereof
-
Application No.: US16318044Application Date: 2017-07-04
-
Publication No.: US11369587B2Publication Date: 2022-06-28
- Inventor: Wu Zhong , Meiyan Yang , Wei Gong , Yuli Wang , Chunsheng Gao , Xinbo Zhou , Song Li
- Applicant: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Applicant Address: CN Beijing
- Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Current Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Current Assignee Address: CN Beijing
- Agency: Banner & Witcoff, Ltd.
- Priority: CN201610559479.1 20160715
- International Application: PCT/CN2017/091650 WO 20170704
- International Announcement: WO2018/010571 WO 20180118
- Main IPC: A61K31/403
- IPC: A61K31/403 ; A61K47/40 ; A61K9/19 ; A61K47/26
Abstract:
The present invention relates to a pharmaceutical composition of Tecovirimat for injection, comprising Tecovirimat as an active ingredient, cyclodextrin and an additive. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.
Public/Granted literature
- US20190336479A1 Injectable Pharmaceutical Composition of Tecovirimat and Preparation Method Thereof Public/Granted day:2019-11-07
Information query
