Invention Grant
- Patent Title: Treatment of RSV with combination product
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Application No.: US16770014Application Date: 2018-12-04
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Publication No.: US11369612B2Publication Date: 2022-06-28
- Inventor: Nina Ysebaert , Nele Isa E. Goeyvaerts , Dirk André Emmy Roymans , Anil Koul
- Applicant: Janssen Sciences Ireland Unlimited Company
- Applicant Address: IE County Cork
- Assignee: Janssen Sciences Ireland Unlimited Company
- Current Assignee: Janssen Sciences Ireland Unlimited Company
- Current Assignee Address: IE County Cork
- Priority: EP17205428 20171205
- International Application: PCT/EP2018/083440 WO 20181204
- International Announcement: WO2019/110563 WO 20190613
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/44 ; A61P31/14 ; A61K31/437

Abstract:
The present invention is directed to the combination of the RSV inhibiting Compound A, i.e. 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, and the RSV inhibiting Compound B, i.e. (1S,2S)-2-[4-[7-cyclopropyl-5-[(1R)-1-methyl-3,4-dihydro-1H-isoquinoline-2-carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluoro-phenyl]cyclopropanecarboxylic acid for treating or ameliorating RSV infection. The invention further relates to the combination product of Compound A and Compound B, a pharmaceutical product comprising Compound A and Compound B, the use of the combination of Compound A and Compound B—or the pharmaceutical product comprising Compound A and Compound B—for the treatment of RSV infection, and a method of treating or ameliorating RSV infection in a subject in need thereof comprising administering the combination of Compound A and Compound B in an effective amount to said subject.
Public/Granted literature
- US20210236496A1 TREATMENT OF RSV WITH COMBINATION PRODUCT Public/Granted day:2021-08-05
Information query
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