Invention Grant
- Patent Title: ILT3 ligand
-
Application No.: US16342582Application Date: 2017-11-10
-
Publication No.: US11370839B2Publication Date: 2022-06-28
- Inventor: Daniel Cua , Holly Cherwinski , Adele Wang , Yi Chen , Barbara Joyce-Shaikh
- Applicant: Daniel Cua , Holly Cherwinski , Adele Wang , Yi Chen , Barbara Joyce-Shaikh , Merck Sharp & Dohme Corp.
- Applicant Address: US CA Boulder Creek; US CA Boulder Creek; US CA San Mateo; US CA San Jose; US CA San Jose; US NJ Rahway
- Assignee: Daniel Cua,Holly Cherwinski,Adele Wang,Yi Chen,Barbara Joyce-Shaikh,Merck Sharp & Dohme Corp.
- Current Assignee: Daniel Cua,Holly Cherwinski,Adele Wang,Yi Chen,Barbara Joyce-Shaikh,Merck Sharp & Dohme Corp.
- Current Assignee Address: US CA Boulder Creek; US CA Boulder Creek; US CA San Mateo; US CA San Jose; US CA San Jose; US NJ Rahway
- Agent Andrew W. Custer; Anna L. Cocuzzo
- International Application: PCT/US2017/060154 WO 20171110
- International Announcement: WO2018/089300 WO 20180517
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00 ; G01N33/542 ; A61K39/00
Abstract:
The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.
Public/Granted literature
- US20190241655A1 ILT3 LIGAND Public/Granted day:2019-08-08
Information query
