According to one embodiment an electric shock self-defence cartridge is provided that includes a distal body in which one or more application means is housed, and a proximal body in which a wire is housed. The proximal body includes coupling means and electric connection means for being joined with the electric shock self-defence device. Compression means is arranged between the distal body and the proximal body for keeping the distal body shifted towards a rest position. The application means is housed in the distal body, such that in use, when the distal body is in contact with an assailant, the distal body shifts with respect to the proximal body from the rest position towards an actuation position in which the application means projects from the distal body to be adhered to the assailant's body.