According to certain implementations, a permissions gateway receives an access request indicating multiple sets of secured data that include high-granularity data stored on multiple secured data repositories. The access request is compared to a permission set with multiple consent parameters, which indicate access types for the secured data. Based on a comparison of the access request to a permission set, the permissions gateway queries, the permission gateway queries a first data repository for a high-granularity dataset that includes a portion of the high-granularity data, and queries a second data repository for a low-granularity dataset that includes a summary of part of the high-granularity data. The permissions gateway generates a multi-granularity response to the access request, based on a combination of the high-granularity dataset and the low-granularity dataset.