A glove with gecko-inspired dry adhesives is provided to greatly reduce the required grasp force on heavy, smooth items. The orientation of the gecko adhesives is designed to increase shear forces between the glove and the object when lifting and manipulating. The invention additionally equips the non-gripping surfaces of the glove (e.g. back and sides) with a non-adhesive microstructure that prevents the glove from accidently adhering to surfaces during unintentional contact, even when touching otherwise sticky materials such as adhesive-coated automotive panels.