The present invention concerns a composition comprising a Lycium barbarum extract or Lycium barbarum polysaccharide in combination with a Moringa oleifera extract and a pharmaceutically acceptable carrier. The composition finds application both in the medical field, in the treatment of actinic lesions, precancerous skin lesions, or non-melanoma skin cancer, and in non-therapeutic applications in the treatment of skin damage caused by exposure to the sun's rays, such as photoaging.