Invention Grant
- Patent Title: Composition, containing sarpogrelate as active ingredient, for preventing or treating sensorineural hearing loss
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Application No.: US16604759Application Date: 2018-04-10
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Publication No.: US11376233B2Publication Date: 2022-07-05
- Inventor: Yun-Hoon Choung , Young Sun Kim , Young-Joon Park
- Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Applicant Address: KR Gyeonggi-do
- Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Current Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Current Assignee Address: KR Gyeonggi-do
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- Priority: KR10-2017-0046741 20170411
- International Application: PCT/KR2018/004184 WO 20180410
- International Announcement: WO2018/190608 WO 20181018
- Main IPC: A61K31/216
- IPC: A61K31/216 ; A61P27/00 ; A61K31/05 ; A61K36/16 ; A61K36/258 ; A61K36/87
Abstract:
The present invention relates to a pharmaceutical composition, containing sarpogrelate or a pharmaceutically acceptable salt thereof as an active ingredient, for preventing, alleviating, or treating sensorineural hearing loss. The sarporgrelate according to the present invention protects against hearing loss caused by noise through the suppression of auditory cell apoptosis and the expression increase of antioxidant enzyme in auditory cells, and thus can be advantageously used in the prevention and alleviation of sensorineural hearing loss.
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