Invention Grant
- Patent Title: RNA-lipid nanoparticle complexes of viral RNA polymerase region and SARS-CoV-2 spike protein region
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Application No.: US17523568Application Date: 2021-11-10
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Publication No.: US11376335B2Publication Date: 2022-07-05
- Inventor: Amit Khandhar , Steven Reed , Malcolm Duthie , Jesse Erasmus , Darrick Carter , Bryan J. Berube
- Applicant: HDT Bio Corp.
- Applicant Address: US WA Seattle
- Assignee: HDT Bio Corp.
- Current Assignee: HDT Bio Corp.
- Current Assignee Address: US WA Seattle
- Agency: Greenberg Traurig LLP
- Main IPC: A61K39/215
- IPC: A61K39/215 ; A61K47/69 ; A61K9/107 ; A61K31/7105 ; A61K31/711 ; A61K47/02 ; A61K47/44 ; A61P31/14 ; A61K9/127 ; C12N15/86 ; A61K9/51 ; A61K31/713 ; A61K39/39 ; A61K49/18 ; B82Y5/00 ; B82Y25/00 ; B82Y30/00 ; B82Y40/00 ; A61K39/00 ; A61K47/54 ; A61K47/10 ; A61K47/26
Abstract:
The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
Public/Granted literature
- US20220096625A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Public/Granted day:2022-03-31
Information query
