Invention Grant
- Patent Title: Systems and methods for sorting T cells by activation state
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Application No.: US16554327Application Date: 2019-08-28
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Publication No.: US11376593B2Publication Date: 2022-07-05
- Inventor: Melissa Caroline Skala , Alexandra Jule Walsh
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Quarles & Brady, LLP
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12N5/00 ; A61K35/17 ; C12N5/0783 ; G01N21/64
Abstract:
Systems and methods for sorting T cells are disclosed. Autofluorescence data is acquired from individual cells. An activation value is computed using one or more autofluorescence endpoints as an input. The one or more autofluorescence endpoints includes NAD(P)H shortest fluorescence lifetime amplitude component (α1).
Public/Granted literature
- US20200070166A1 SYSTEMS AND METHODS FOR SORTING T CELLS BY ACTIVATION STATE Public/Granted day:2020-03-05
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