Invention Grant
- Patent Title: Pyridopyrimidine compounds acting as mTORC 1/2 dual inhibitors
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Application No.: US16760740Application Date: 2018-11-02
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Publication No.: US11377444B2Publication Date: 2022-07-05
- Inventor: Kevin X Chen , Zhaoguo Chen , Li Zhang , Yanxin Yu , Kai Zhou , Boyu Hu , Xiaofei Wang , Guoping Hu , Jian Li , Shuhui Chen
- Applicant: MEDSHINE DISCOVERY INC.
- Applicant Address: CN Jiangsu
- Assignee: MEDSHINE DISCOVERY INC.
- Current Assignee: MEDSHINE DISCOVERY INC.
- Current Assignee Address: CN Jiangsu
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: CN201711080753.8 20171106,CN201810136962.8 20180209,CN201810661825.6 20180625
- International Application: PCT/CN2018/113683 WO 20181102
- International Announcement: WO2019/085996 WO 20190509
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; C07D519/00
Abstract:
Disclosed are a series of pyridopyrimidine compounds and a use of same in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors, and specifically disclosed is a use of the compounds as shown in formula (IV), tautomers thereof or pharmaceutically acceptable salts thereof in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors.
Public/Granted literature
- US20200339568A1 PYRIDOPYRIMIDINE COMPOUNDS ACTING AS MTORC 1/2 DOUBLE-KINASE INHIBITORS Public/Granted day:2020-10-29
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