Invention Grant
- Patent Title: Glutamate transporter activators and methods using same
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Application No.: US16477946Application Date: 2018-01-16
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Publication No.: US11377452B2Publication Date: 2022-07-05
- Inventor: Sandhya Kortagere , Andreia C. K. Mortensen , Ole V. Mortensen , Joseph M. Salvino
- Applicant: DREXEL UNIVERSITY
- Applicant Address: US PA Philadelphia
- Assignee: DREXEL UNIVERSITY
- Current Assignee: DREXEL UNIVERSITY
- Current Assignee Address: US PA Philadelphia
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Domingos J. Silva
- International Application: PCT/US2018/013867 WO 20180116
- International Announcement: WO2018/132829 WO 20180719
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61P25/28 ; C07D401/14 ; C07D403/04 ; C07D405/14

Abstract:
The present invention provides compounds useful for treating, ameliorating or preventing a disease or disorder that is caused, induced or characterized by abnormal reduction in glutamate transporter activity or abnormal increase in extracellular CNS glutamate concentration in a subject. In certain embodiments, the compound stimulates a glutamate transporter.
Public/Granted literature
- US20200255445A1 Glutamate Transporter Activators and Methods Using Same Public/Granted day:2020-08-13
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