Invention Grant
- Patent Title: Differentiation of human embryonic stem cells into single hormonal insulin positive cells
-
Application No.: US16435428Application Date: 2019-06-07
-
Publication No.: US11377640B2Publication Date: 2022-07-05
- Inventor: Alireza Rezania
- Applicant: Janssen Biotech, Inc.
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agency: Klarquist Sparkman, LLP
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides methods to produce a population of cells, wherein greater than 10% of the cells in the population express markers characteristic of single hormonal pancreatic beta cells.
Public/Granted literature
- US20190292523A1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO SINGLE HORMONAL INSULIN POSITIVE CELLS Public/Granted day:2019-09-26
Information query
