Invention Grant
- Patent Title: Oligonucleotides for treatment of angiopoietin like 4 (ANGPTL4) related diseases
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Application No.: US17476317Application Date: 2021-09-15
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Publication No.: US11377658B2Publication Date: 2022-07-05
- Inventor: Omri Gottesman , Shannon Bruse , Brian Cajes , David Lewis , David Rozema
- Applicant: EMPIRICO INC.
- Applicant Address: US CA San Diego
- Assignee: EMPIRICO INC.
- Current Assignee: EMPIRICO INC.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
Provided are compositions comprising an oligonucleotide that targets Angiopoietin-like 4 (ANGPTL4). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating a metabolic or cardiovascular disorder by providing an oligonucleotide that targets ANGPTL4 to a subject in need thereof.
Public/Granted literature
- US20220002731A1 OLIGONUCLEOTIDES FOR TREATMENT OF ANGIOPOIETIN LIKE 4 (ANGPTL4) RELATED DISEASES Public/Granted day:2022-01-06
Information query
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