Invention Grant
- Patent Title: Methods and kits for diagnosing kawasaki disease and methods for treating kawasaki disease
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Application No.: US16196092Application Date: 2018-11-20
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Publication No.: US11377691B2Publication Date: 2022-07-05
- Inventor: Ying-Hsien Huang , Ho-Chang Kuo
- Applicant: Chang Gung Memorial Hospital, Kaohsiung
- Applicant Address: TW Kaohsiung
- Assignee: Chang Gung Memorial Hospital, Kaohsiung
- Current Assignee: Chang Gung Memorial Hospital, Kaohsiung
- Current Assignee Address: TW Kaohsiung
- Agency: Pilloff Passino & Cosenza LLP
- Agent Sean A. Passino; Rachel K. Pilloff
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6883 ; C12Q1/6816 ; C12Q1/6851 ; A61P9/00 ; A61K39/00

Abstract:
The present invention relates to methods that use novel biomarkers for diagnosing and/or treating Kawasaki diseases. The novel biomarkers of the invention show altered cytosine methylations state of certain CpG loci in subject with Kawasaki Disease relative to subject without Kawasaki diseases. Also provided are kits comprising at least one primer or reagent specific for the altered cytosine methylation state of certain CpG loci to detect Kawasaki Disease.
Public/Granted literature
- US20190153081A1 METHODS AND KITS FOR DIAGNOSING KAWASAKI DISEASE AND METHODS FOR TREATING KAWASAKI DISEASE Public/Granted day:2019-05-23
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