An escape-prevention arrow includes an arrow body, a hook and a restraining wire. The arrow body has two ends and a buckling part, and the two ends are an arrow tail and an arrowhead respectively. The buckling pan is disposed near the arrowhead. The hook is disposed on the buckling part and can be separated from the arrow body when being impacted. The restraining wire is connected between the hook and the arrow body. When the arrow formed by the configuration of the arrow body, the hook and the restraining wire hits an animal, the hook is able to hook a tree, so as to restrain the animal from escaping. In this way, a hunter may have enough time to knife the animal, so as to quickly kill the animal to reduce its pain, thereby greatly solving the problem that the killing efficiency of bow is insufficient.