An array substrate, a display panel, and a display device are provided. In the array substrate, each of the pixel units includes a first pixel region and a second pixel region. The array substrate includes an alignment film located on the base substrate, a plurality of first electrode strips located in the first pixel region, and a plurality of second electrode strips located in the second pixel region. The alignment film has a first alignment direction and a second alignment direction. An extension direction of the first electrode strip and the first alignment direction have a first included angle, an extension direction of the second electrode strip and the second alignment direction have a second included angle, and the first included angle is less than the second included angle.