In various embodiments, a Data Processing System for Generating Interactive User Interfaces and Interactive Game Systems Based on Spatiotemporal Analysis of Video Content may be configured to: (1) enable a user to select one or more players participating in a substantially live (e.g., live) sporting or other event; (2) determine scoring data for each of the one or more selected players during the sporting or other event; (3) track the determined scoring data; (4) generate a custom (e.g., to the user) user interface that includes the scoring data; and (5) display the custom user interface over at least a portion of a display screen (e.g., on a mobile computing device) displaying one or more video feeds of the sporting or other event. In this way, the system may be configured to convert a video feed of a sporting event into an interactive game.