Invention Grant
- Patent Title: Ionizable compounds and compositions and uses thereof
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Application No.: US16228054Application Date: 2018-12-20
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Publication No.: US11384051B2Publication Date: 2022-07-12
- Inventor: Roger Adami , Hao Bai , John Gaudette , Bharat Majeti , Seiji Nukui , Kwok Yin Tsang , Hai Wang , Haiqing Yin , Wenbin Ying
- Applicant: Nitto Denko Corporation
- Applicant Address: JP Osaka
- Assignee: Nitto Denko Corporation
- Current Assignee: Nitto Denko Corporation
- Current Assignee Address: JP Osaka
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: A61K31/713
- IPC: A61K31/713 ; A61K31/7105 ; A61K9/127 ; A61K9/51 ; A61K47/16 ; A61K47/22 ; A61K47/24 ; C07C271/16 ; C07D205/04 ; C07D207/12 ; C07C237/16 ; C07D207/09 ; C07D211/86 ; C07D211/82 ; C07D211/74 ; C07F9/06 ; C07F9/10 ; C07C237/08 ; C07C237/50
Abstract:
This invention includes ionizable compounds, and compositions and methods of use thereof. The ionizable compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, this invention relates to compounds, compositions and methods for providing nanoparticles to encapsulate active agents, such as nucleic acid agents, and to deliver and distribute the active agents to cells, tissues, organs, and subjects.
Public/Granted literature
- US20190127318A1 IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF Public/Granted day:2019-05-02
Information query
