A method and device for signal transmission are provided. The method includes that: a receiving node receives a request-to-send (RTS) signal from a sending node; the receiving node determines a sending power and/or a signal format of a clear-to-send (CTS) signal; and the receiving node sends, according to the sending power and/or the signal format, the CTS signal to the sending node. Accordingly, after the sending node sends the RTS signal to the receiving node, the receiving node can determine the sending power and/or the signal format of the RTS signal, and send the CTS signal to the sending node based on the sending power and/or the signal format.