Invention Grant
- Patent Title: Process for the preparation of sterile ophthalmic aqueous fluticasone propionate form a nanocrystals suspensions
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Application No.: US16934807Application Date: 2020-07-21
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Publication No.: US11406596B2Publication Date: 2022-08-09
- Inventor: Jean-Michel Bukowski , Akshay Nadkarni , José L. Boyer , Brigitte Duquesroix-Chakroun , Tomas Navratil
- Applicant: Nicox Ophthalmics, Inc.
- Applicant Address: US NC Durham
- Assignee: Nicox Ophthalmics, Inc.
- Current Assignee: Nicox Ophthalmics, Inc.
- Current Assignee Address: US NC Durham
- Agency: ArentFox Schiff LLP
- Main IPC: A61K9/08
- IPC: A61K9/08 ; A61P27/02 ; A61K9/00 ; A61K31/567 ; A61K47/02 ; A61K47/10 ; A61K47/18 ; A61K47/26 ; A61K47/38 ; B82Y5/00
Abstract:
A process of manufacturing sterile topical ophthalmic aqueous nanosuspensions of nanocrystals of fluticasone propionate Form A. The sterile topical ophthalmic nanosuspensions may be used in the treatment of eye inflammation conditions such as blepharitis, posterior blepharitis, Meibomian gland dysfunction and dry eye through topical administration of said nanosuspensions to eyelids, eyelashes and eyelid margin.
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