Invention Grant
- Patent Title: Stabilized radiolabeled anti-CD45 immunoglobulin compositions
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Application No.: US16298202Application Date: 2019-03-11
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Publication No.: US11406724B2Publication Date: 2022-08-09
- Inventor: Kaushik J. Dave , Shubh D. Sharma
- Applicant: Kaushik J. Dave , Shubh D. Sharma
- Applicant Address: US NJ Edison; US NJ Cranbury
- Assignee: Kaushik J. Dave,Shubh D. Sharma
- Current Assignee: Kaushik J. Dave,Shubh D. Sharma
- Current Assignee Address: US NJ Edison; US NJ Cranbury
- Agency: Dentons Cohen & Grigsby P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K51/10 ; A61K35/28 ; C07K16/28 ; C07K16/30 ; A61K9/00 ; A61K47/22 ; A61K47/32 ; A61K47/42 ; A61K35/12 ; A61K39/00
Abstract:
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.
Public/Granted literature
- US20190192702A1 STABILIZED RADIOLABELED ANTI-CD45 IMMUNOGLOBULIN COMPOSITIONS Public/Granted day:2019-06-27
Information query
