- Patent Title: RIP1 inhibitory compounds and methods for making and using the same
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Application No.: US17012779Application Date: 2020-09-04
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Publication No.: US11407736B2Publication Date: 2022-08-09
- Inventor: Yan Chen , Jiaxin Yu , Simon Shaw , Ihab Darwish , Vanessa Taylor , Somasekhar Bhamidipati , Zhushou Luo , Rao Kolluri
- Applicant: Rigel Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Gabriel Magallanes
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D491/048 ; C07D495/04 ; C07D513/04 ; A61K31/55 ; A61K31/5517 ; A61K31/54 ; C07D401/14 ; C07D401/12 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D471/08 ; C07D487/04 ; C07D491/107 ; A61K31/553 ; C07D267/02 ; C07D413/12 ; C07D413/14 ; C07D493/04

Abstract:
Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.
Public/Granted literature
- US20210070743A1 RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME Public/Granted day:2021-03-11
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