Invention Grant
- Patent Title: Triptolide derivative and preparation method therefor and use thereof
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Application No.: US16757799Application Date: 2018-04-18
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Publication No.: US11407783B2Publication Date: 2022-08-09
- Inventor: Fei Xiao , Bo Qiu , Peng Zhang
- Applicant: Cinkate Pharmaceutical Intermediates Co., Ltd. , Cinkate Pharm Tech (Shanghai) Co., Ltd.
- Applicant Address: CN Shanghai; CN Shanghai
- Assignee: Cinkate Pharmaceutical Intermediates Co., Ltd.,Cinkate Pharm Tech (Shanghai) Co., Ltd.
- Current Assignee: Cinkate Pharmaceutical Intermediates Co., Ltd.,Cinkate Pharm Tech (Shanghai) Co., Ltd.
- Current Assignee Address: CN Shanghai; CN Shanghai
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: CN201810283385.5 20180402
- International Application: PCT/CN2018/083525 WO 20180418
- International Announcement: WO2019/192031 WO 20191010
- Main IPC: C07J73/00
- IPC: C07J73/00 ; A61K9/00 ; A61P35/00 ; A61P37/06
Abstract:
A triptolide derivative, a preparation method therefor, and a method for use thereof are described. The triptolide derivative has the structure as shown in general formula I, and the definition of each substituent is as described in the description and claims. The triptolide derivative has improved immunosuppressive activity and anti-tumor activity, low toxicity and high safety, thus having good development and application prospects.
Public/Granted literature
- US20210238221A1 TRIPTOLIDE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF Public/Granted day:2021-08-05
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