Invention Grant
- Patent Title: Intermittent starvation techniques to prolong functional lifetime of liver cells in culture
-
Application No.: US16119399Application Date: 2018-08-31
-
Publication No.: US11407979B2Publication Date: 2022-08-09
- Inventor: Salman R. Khetani , Matthew D. Davidson
- Applicant: Colorado State University Research Foundation
- Applicant Address: US CO Fort Collins
- Assignee: Colorado State University Research Foundation
- Current Assignee: Colorado State University Research Foundation
- Current Assignee Address: US CO Fort Collins
- Agency: Polsinelli PC
- Main IPC: C12N15/88
- IPC: C12N15/88 ; C12N5/071 ; G01N33/50
Abstract:
The present disclosure relates to compositions and methods for culturing a population of hepatocytes in vitro, comprising co-culturing the population of hepatocytes with at least one non-parenchymal cell population and incubating the co-culture in culture medium, wherein the co-culture is periodically incubated in culture medium that does not comprise serum (serum-free culture medium).
Public/Granted literature
- US20190071638A1 INTERMITTENT STARVATION TECHNIQUES TO PROLONG FUNCTIONAL LIFETIME OF LIVER CELLS IN CULTURE Public/Granted day:2019-03-07
Information query
IPC分类:
