A wind turbine and method are provided for defining a plurality of thrust limits for the wind turbine located at a site and having a rotor with rotor blades, wherein the thrust limits define values of aerodynamic thrust on the rotor not to be exceeded in operation. The method includes providing a wind speed distribution representative for the site and defining one or more isolines of constant turbulence probability representing a turbulence parameter as a function of wind speed. The isolines correspond to quantile levels of turbulence of the wind speed distribution and the turbulence parameter is indicative of wind speed variation. The turbulence parameter is determined by continuously measuring wind speed upstream of the rotor with an active sensing system and calculating the wind speed variations from the measured wind speed. Turbulence ranges are defined with respect to the isolines and thrust limits are defined for the turbulence ranges.