Electronic device for regulating a thermo-fluidic system for a building, including a heating/cooling system including mixing valves adapted to control flows of hot/cold water within said heating/cooling system, the device including a control unit adapted to: receive a main signal from a building management system; receive a predefined reference signal representative of a desired parameter for the building; receive environmental signals from environmental sensors placed in the building and adapted to measure environmental parameters of said building; issue a control signal towards an actuator associated with a respective mixing valve in order to modify the opening or closing thereof.