A biological material measurement device 80 comprises; a first light source emitting a first light; an ATR prism 20 including a front surface and a back surface and allowing the first light made incident from one end to be transmitted therethrough and emitted from the other end; a hyperbolic metamaterial layer 90 including a front surface and a back surface and arranged on the front surface of the ATR prism 20 such that the back surface of the hyperbolic metamaterial layer is in contact therewith; and a first light detector detecting the first light emitted from the ATR prism 20. An amount of a biological material in a living body is measured from the detected first light.