Invention Grant
- Patent Title: Selective near-infrared optical imaging of necrotic cells and simultaneous cell fixing and counter staining with metallacrown complexes
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Application No.: US16547396Application Date: 2019-08-21
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Publication No.: US11408893B2Publication Date: 2022-08-09
- Inventor: Ivana Martinic , Tu Ngoc Nguyen , Svetlana V. Eliseeva , Vincent L. Pecoraro , Stéphane Petoud
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Applicant Address: US MI Ann Arbor; FR Paris
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: US MI Ann Arbor; FR Paris
- Agency: Dierker & Kavanaugh, P.C.
- Main IPC: G01N33/58
- IPC: G01N33/58 ; C07F3/06 ; C07F5/00 ; G01N1/30 ; G01N21/33 ; G01N21/64
Abstract:
A method for selective labelling of necrotic cells including incubating the cells in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand.
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