Invention Grant
- Patent Title: Secreted P-glycoprotein is a non-invasive biomarker of chronic rhinosinusitis
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Application No.: US16070053Application Date: 2017-01-13
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Publication No.: US11408900B2Publication Date: 2022-08-09
- Inventor: Benjamin S. Bleier , Angela Nocera
- Applicant: Massachusetts Eye and Ear Infirmary
- Applicant Address: US MA Boston
- Assignee: Massachusetts Eye and Ear Infirmary
- Current Assignee: Massachusetts Eye and Ear Infirmary
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2017/013418 WO 20170113
- International Announcement: WO2017/123933 WO 20170720
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/68 ; A61K9/00 ; A61K45/06 ; A61K31/277 ; A61K31/4725 ; A61K31/496 ; A61K31/4164 ; A61K31/4545 ; A61K31/473 ; A61K31/55 ; A61K38/13 ; A61K38/00
Abstract:
Methods for identifying and optionally treating subjects, e.g., subjects who have Chronic Rhinosinusitis (CRS), based on the detection of elevated levels of soluble P-glycoprotein in nasal secretions. The methods of treatment can include administration of a therapeutically effective amount of a P-glycoprotein inhibitor.
Public/Granted literature
- US20190086426A1 Secreted P-glycoprotein is a Non-Invasive Biomarker of Chronic Rhinosinusitis Public/Granted day:2019-03-21
Information query
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