Systems and methods for predictive technology incident reduction are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for predictive technology incident reduction may include: (1) receiving a change record for a proposed change to a computer application or a computer network infrastructure; (2) analyzing the potential change for an adverse potential cross impact with another computer application or a computer system; (3) predicting a probability of failure and an impact of the proposed change using a model; (4) in response to a low predicted probability of failure, or a high predicted probability of failure with a low predicted impact: approving the proposed change; and implementing the proposed change; and (5) in response to a high predicted probability of failure and a high predicted impact, rejecting the proposed change.