Systems and methods of WLAN communication including efficient spatial reuse mechanisms for relay transmissions between a repeater network and non-AP STAs in OFDMA. The non-AP STAs are grouped based on their connectivity with the individual repeaters and the radio coverage regions of the repeaters. Each group is either a non-overlapping group with the constituent non-AP STAs located in a non-overlapping coverage region of a particular repeater, or an overlapping group with the constituent non-AP STAs located in an overlapping coverage region of two or more repeaters. Based on the grouping, certain RUs (or subchannels) are reused for multiple groups without causing inter-group interference, thereby expanding the bandwidths used in the relay operations. RU allocation based on grouping can be used in combination with transmit power adjustment to achieve efficient spatial reuse in OFDMA.