Invention Grant
- Patent Title: Pharmaceutical composition for treating cancer comprising lactate metal salt
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Application No.: US16693218Application Date: 2019-11-22
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Publication No.: US11413261B2Publication Date: 2022-08-16
- Inventor: Hwan Mook Kim , Keun Yeong Jeong , Jae Jun Sim , Yeong Su Jang
- Applicant: METIMEDI PHARMACEUTICALS CO., LTD
- Applicant Address: KR Incheon
- Assignee: METIMEDI PHARMACEUTICALS CO., LTD
- Current Assignee: METIMEDI PHARMACEUTICALS CO., LTD
- Current Assignee Address: KR Incheon
- Agency: ArentFox Schiff LLP
- Priority: KR10-2014-0192158 20141229,KR10-2015-0142828 20151013
- Main IPC: A61K31/19
- IPC: A61K31/19 ; A61K31/436 ; A61K31/404 ; A61K31/4745 ; A61K31/506 ; A61K31/513 ; A61K45/06 ; A61K9/00 ; A61K33/34 ; A61K9/70 ; A61K9/08 ; A61K31/191 ; A61K33/30 ; A61K33/04 ; A61K33/06 ; A61K9/48 ; A23L33/00 ; A23L33/16 ; A61K31/337 ; A61K31/44 ; A61K31/517 ; A61K31/519 ; A61K31/5377 ; A61K31/555 ; A61K39/395 ; A61N5/10

Abstract:
The present invention relates to: a pharmaceutical composition for treating cancer containing, as an active ingredient, a metal lactate salt, which can be dissociated, in cancer cells, into lactate capable of effectively inhibiting actions such as proliferation, invasion, and metastasis of cancer cells by disturbing the metabolic processes of cancer cells; a pharmaceutical composition for inhibiting cancer metastasis; a food composition for alleviating cancer; and a method for treating cancer and a method for inhibiting cancer matastasis, both methods comprising a step of administering the lactate metal salt. The metal lactate salts of the present invention as disclosed inhibit the growth of cancer cells and induce the death of cancer cells by disturbing the metabolic processes in the main energy production pathways of cancer, and inhibit the expression of factors inducing resistance against radiation exposure, while having no side effects. Therefore, the lactate metal salt can be widely utilized in a more effective anti-cancer therapy.
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