Invention Grant
- Patent Title: Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
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Application No.: US15444151Application Date: 2017-02-27
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Publication No.: US11414489B2Publication Date: 2022-08-16
- Inventor: Sanna Rosengren , H. Michael Shepard , Curtis B. Thompson
- Applicant: HALOZYME, INC.
- Applicant Address: US CA San Diego
- Assignee: HALOZYME, INC.
- Current Assignee: HALOZYME, INC.
- Current Assignee Address: US CA San Diego
- Agency: Dentons US LLP
- Agent Stephanie Seidman
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K38/47 ; A61K39/395 ; C12N9/26 ; A61K9/00 ; A61K31/573 ; A61P35/00 ; C12N15/00 ; A61K47/60 ; A61K39/00 ; A61K9/127
Abstract:
Provided are methods of treatments with combinations or compositions containing a soluble hyaluronidase, such as a polymer-modified hyaluronidase, and an immune checkpoint inhibitor treating cancers, including solid and non-solid tumors. The combinations and compositions also are provided.
Public/Granted literature
- US20180044419A9 COMBINATION THERAPY WITH A HYALURONAN-DEGRADING ENZYME AND AN IMMUNE CHECKPOINT INHIBITOR Public/Granted day:2018-02-15
Information query
