A submersible pump system may include a perforated casing lining a wellbore adjacent to a first formation and a second formation. Additionally, a production tubing may be hanging in the wellbore to extend past the first formation and into the second formation to form a fluid conduit from a surface to the second formation. Further, an electrical submersible pump may be coupled to the production tubing and be oriented upside-down to have one or more fluid intakes at an upper end of the electrical submersible pump and one or more fluid outlets at a lower end of the electrical submersible pump. The electrical submersible pump may be positioned downhole in the wellbore between the first formation and the second formation. The upside-down electrical submersible pump may be configured to extract fluid from the first formation and inject the extracted fluid into the second formation with the production tubing.