A surgical system including an endoscopic navigation catheter, at least one laparoscopic access port, a laparoscopic tool, and an endoscopic tool. The endoscopic navigation catheter is configured for navigation of a luminal network to an area of interest. The at least one laparoscopic access port is placed adjacent to the area of interest. The laparoscopic tool is configured for insertion through the at least one laparoscopic access port, and the endoscopic tool is configured for insertion through the endoscopic navigation catheter. The laparoscopic tool and endoscopic tool enable a combined laparoscopic and endoscopic approach to the area of interest.