Invention Grant
- Patent Title: Stabilized tacrolimus composition
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Application No.: US16188805Application Date: 2018-11-13
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Publication No.: US11419823B2Publication Date: 2022-08-23
- Inventor: Nikolaj Skak , Per Holm
- Applicant: Veloxis Pharmaceuticals A/S
- Applicant Address: DK Copenhagen
- Assignee: Veloxis Pharmaceuticals A/S
- Current Assignee: Veloxis Pharmaceuticals A/S
- Current Assignee Address: DK Copenhagen
- Agency: Blank Rome LLP
- Priority: DKPA-2010-00137 20100217
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K9/14 ; A61K31/436
Abstract:
The invention relates to a stable pharmaceutical composition comprising comprising a solid dispersion of tacrolimus in a vehicle further comprising a stabilizing agent capable of providing a pH below 7 in the composition, as measured after re-dispersion in water, and preventing or reducing the formation upon storage of major degradation products of tacrolimus, in particular the 8-epitacrolimus.
Public/Granted literature
- US20190282504A1 STABILIZED TACROLIMUS COMPOSITION Public/Granted day:2019-09-19
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