- Patent Title: Surface-modified mesoporous silica nanoparticle for blood-brain barrier penetration,tumor targeting and cancer metastasis treatment, methods of production and uses thereof
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Application No.: US16864017Application Date: 2020-04-30
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Publication No.: US11419826B2Publication Date: 2022-08-23
- Inventor: Cheng-Hsun Wu , Yi-Ping Chen , Si-Han Wu , Chung-Yuan Mou
- Applicant: NANO TARGETING & THERAPY BIOPHARMA INC.
- Applicant Address: TW Taipei
- Assignee: NANO TARGETING & THERAPY BIOPHARMA INC.
- Current Assignee: NANO TARGETING & THERAPY BIOPHARMA INC.
- Current Assignee Address: TW Taipei
- Agency: Prosyla Group PC
- Main IPC: A61K9/51
- IPC: A61K9/51 ; A61K47/60 ; A61K41/00 ; A61K45/06 ; B82Y5/00
Abstract:
The present disclosure relates to mesoporous silica nanoparticles (MSNs) with specific modifications as drug delivery systems containing both tumor targeting and blood-brain barrier (BBB) penetration properties suitable for cancer treatment and/or CNS disease treatment. The present disclosure also relates to method of preparing MSNs and the MSNs prepared by the method as described herein.
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