Invention Grant
- Patent Title: Peptide derivatives and therapeutic activity thereof
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Application No.: US16958336Application Date: 2018-12-19
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Publication No.: US11420943B2Publication Date: 2022-08-23
- Inventor: GianPaolo Negrisoli , Stefania Gagliardi , Almin Silnovic , Clelia Dallanoce , Marco De Amici , Renato Canevotti
- Applicant: FLAMMA S.P.A.
- Applicant Address: IT Chignolo d'Isola
- Assignee: FLAMMA S.P.A.
- Current Assignee: FLAMMA S.P.A.
- Current Assignee Address: IT Chignolo d'Isola
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: IT102017000149628 20171227
- International Application: PCT/IB2018/060332 WO 20181219
- International Announcement: WO2019/130164 WO 20190704
- Main IPC: C07D233/64
- IPC: C07D233/64
Abstract:
Disclosed are peptide or pseudopeptide derivatives containing a nitrogenous heterocyclic residue with blocking activity against the by-products of lipid oxidative stress, and in particular of unsaturated aldehydes such as malondialdehyde and 4-hydroxy-trans-2-nonenal (HNE).
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